Used to aid ultrasound in the screening of right-to-left blood shunting (RLS) within the heart.
Conditions
Interventions
Test group:Ultrasound contrast injection device.
Control group:Artificial foaming test inspection.
Sponsors
The First Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 16 to 65 years old, no gender restrictions. 2. Clinical suspicion of right-to-left shunt: presence of patent foramen ovale (PFO) or PFO-related stroke, transient ischemic attack (TIA), or premonitory symptoms of migraine. 3. Ability to perform a right-sided cardiac echocardiogram (cTTE) or transcranial Doppler ultrasound-angiography (cTCD) assessment for evaluation of right-to-left shunt. 4. Ability to perform the Valsalva maneuver. I understand the purpose of the trial, voluntarily agree to participate in it, and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with severe multi-organ failure. 2. Suffering from intellectual disabilities or severe hearing impairments. 3. Individuals who, for various reasons, are unable to receive intravenous administration of physiologic saline. 4. Those who are unable to administer the contrast agent due to issues related to puncturing blood vessels. 5. Female participants during pregnancy and breastfeeding. The researchers determined that there were other circumstances under which an individual would not be suitable for participation in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consistency rate of right-to-left shunt detection.;Right-to-left shunt grading.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of the procedure.;Diagnostic success rate.; | — |
Countries
China
Contacts
Public ContactJie Ma
The First Hospital of Hebei Medical University
Outcome results
None listed