COVID-19
Conditions
Interventions
COVID-19 survivors:Digital Mental Health (DMH) platform
Non-COVID Control:Digital Mental Health (DMH) platform
Sponsors
The Chinese University of Hong Kong
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: COVID-19 survivors and age- and sex-matched non-COVID controls: Self-reported: Patient Health Questionnaire-9 (PHQ-9) >= 10 (depression), Generalized Anxiety Disorder-7 (GAD-7) >= 10 (anxiety), or Insomnia Severity Index (ISI) >= 14 (insomnia) Meet clinical diagnostic criteria for depression, anxiety, or insomnia disorders, as assessed by the Mini-international Neuropsychiatric Interview (MINI) and Structured Diagnostic Interview for Sleep Patterns and Disorders (DISP) based on DSM-5 criteria Non-COVID Control Group: Age- and sex-matched controls with comparable psychiatric distress will be included for balanced demographics During the COVID pandemic, even non-COVID subjects may experience significant distress Controlling for distress level—through psychometric ratings and clinical diagnosis—enables better comparison of gut dysbiosis’ moderation effect on intervention
Exclusion criteria
Exclusion criteria: Age<18
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index;Patient Health Questionnaire-9 ;General Anxiety Disorder-7 (GAD-7) ;The Clinical Global Impressions Scale (CGI-I); | — |
Secondary
| Measure | Time frame |
|---|---|
| Gut microbiota;Epworth Sleepiness Scale;Chalder Fatigue Scale-11;World Health Organization Quality-of-Life Scale; | — |
Countries
China
Contacts
Public ContactDr. CHAN Ngan Yin
The Chinese University of Hong Kong
Outcome results
None listed