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Research on peripheral blood prognostic biomarkers for early neurological deterioration in acute ischemic stroke based on multi-omics technology

Research on peripheral blood prognostic biomarkers for early neurological deterioration in acute ischemic stroke based on multi-omics technology

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123218
Enrollment
Unknown
Registered
2026-04-22
Start date
2026-04-28
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke

Interventions

Early Neurological Deterioration Group:None
Control Group:None

Sponsors

Beijing Tsinghua Changgung Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years; 2.Symptomatic acute ischemic stroke (including first/recurrent stroke); 3.Successful completion of peripheral blood sample collection for blood tests within 24 hours of admission (for patients undergoing thrombolysis/endovascular treatment, blood samples thrombolysis/endovascular treatment should be collected), including 2 tubes of EDTA-anticoagulated blood and 1 tube of sodium citrate-anticoagulated blood; for hospitalized patients, blood samples collected at multiple time points as needed after admission, including 2 tubes of EDTA-anticoagulated blood and 1 tube of sodium citrate-anticoagulated blood. 4.Detailed clinical data recording.

Exclusion criteria

Exclusion criteria: 1.Hemorrhagic stroke; 2.Comorbid serious systemic diseases that may affect life expectancy, including cancer, cardiopulmonary or hepatic/renal failure, etc.; 3.Infectious disease within 14 days prior to symptom onset; 4.Comorbid immunosuppression or use of immunosuppressive drugs; 5.Incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
Early Neurological Deterioration in Retrospective study;Early Neurological Deterioration in Prospective study;

Secondary

MeasureTime frame
Secondary indicators are not included in retrospective study.;Secondary indicators are not included in prospective study.;

Countries

China

Contacts

Public ContactJian Wu

Beijing Tsinghua Changgung Hospital

gcsa04112@btch.edu.cn+86 134 6676 6485

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026