Scoliosis surgery
Conditions
Interventions
Trial Group:Dorsal root ganglion blockade with 0.15% ropivacaine (300 ml, 4-10 ml/h)
postoperative patient-controlled intravenous analgesia (hydromorphone 10 mg + ondansetron 16 mg diluted to 100 mL with normal saline, bolus dose 1 ml, lockout interval 10 min, maximum hourly dose 6 ml
Control Group:No dorsal root ganglion blockade
Sponsors
University of Hong Kong–Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 60 years old; 2. ASA grades I to III; 3. All patients were diagnosed with spinal curvature; 4. Patients scheduled for spinal curvature osteotomy and correction surgery, and the osteotomy range was >= 4 segments; 5. The patients had clear consciousness and stable vital signs.
Exclusion criteria
Exclusion criteria: 1. There is a problem with coagulation function; 2. There is an allergy to anesthetic drugs; 3. Patients with severe liver and kidney dysfunction; 4. Patients with infectious diseases; 5. Patients with severe cardiovascular and cerebrovascular diseases; 6. Patients who have long-term abuse of sedative drugs, opioid drugs, and drugs that affect cognitive function; 7. Patients who experienced severe unexpected situations such as massive bleeding during the operation, making the surgery unable to proceed normally; 8. Patients with a history of spinal surgery in the same area; 9. Patients who experienced a significant decrease in somatosensory/motor evoked potentials during the operation or suspected spinal cord/nerve root injury; 10. Patients who cannot cooperate with the researchers due to cognitive impairment, psychological or mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The dosage of analgesic drugs that needs to be supplemented during the anesthesia recovery period; | — |
Secondary
| Measure | Time frame |
|---|---|
| The pain numerical rating score at rest within 24 hours after surgery;Dynamic pain NRS score;The total consumption of analgesic drugs in the analgesic pump, the total number of presses and the number of analgesic rescue within 72 hours after surgery.;The occurrence rates of nausea, vomiting, skin itching, respiratory depression and urinary retention within 72 hours after the operation;The sleep quality score 3 days after the operation; | — |
Countries
China
Contacts
Public ContactWang Weixuan
University of Hong Kong–Shenzhen Hospital
Outcome results
None listed