Respiratory Diseases
Conditions
Interventions
Observation group(Remimazolam Besylate):None
Sponsors
Chengdu Third People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.The subject is ineligible for trial participation if they do NOT meet ALL of the following criteria: (1) Aged 18 years or older, regardless of gender; (2) Non-intubated patients in the ICU requiring fiberoptic bronchoscopy; (3) The patient or their legal guardian voluntarily agrees to participate in this study and provides signed informed consent.
Exclusion criteria
Exclusion criteria: 1.The subject is ineligible for trial participation if ANY of the following criteria applies: (1) Allergy to remimazolam besylate or any component of the investigational or concomitant medications; (2) Severe circulatory instability (e.g., MAP 20 mmHg) or status epilepticus; (4) Pregnancy or lactation; (5) Electrocardiogram indicating a heart rate < 50 beats per minute; (6) History of alcohol or drug abuse, or chronic pain requiring long-term use of analgesics or sedatives; (7) History of severe hepatic or renal dysfunction, metabolic diseases, or related conditions; (8) Participation in any other investigational clinical trial within 3 months prior to screening; (9) Expected survival time < 48 hours. (10) Inability to obtain informed consent or authorization; (11) Other conditions considered by the investigators to be not included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RASS score; | — |
Countries
China
Contacts
Public ContactZeng Wei
Chengdu Third People's Hospital
Outcome results
None listed