cardiotoxicity
Conditions
Interventions
Cardiotoxicity group:No intervention
Non-cardiotoxicity group:No intervention
Sponsors
The Fifth Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Breast cancer was confirmed by pathological examination and clinical imaging studies. 2. Patients were diagnosed with stage I-III breast cancer according to the American Joint Committee on Cancer (AJCC) staging criteria.
Exclusion criteria
Exclusion criteria: 1. History of other malignancies; 2. Prior history of chest radiotherapy; 3. Prior exposure to anthracyclines or other neoadjuvant therapies, or life expectancy less than 12 months; 4. Participation in oncological clinical trials; 5. Past medical history: cardiac adverse events of grade 3 or higher; 6. Pregnancy and/or lactation; 7. History of arrhythmia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cancer therapy-related cardiac dysfunction (CTRCD); | — |
Secondary
| Measure | Time frame |
|---|---|
| ECG examination;Left Ventricular Ejection Fraction;Biological markers (cTnI/cTnT, BNP, CK-MB,), etc.;Clinical heart failure event; | — |
Countries
China
Contacts
Public ContactYu Hui
The Fifth Affiliated Hospital of Zhengzhou University
Outcome results
None listed