Liver Cancer
Conditions
Interventions
Fospropofol group:In the fospropofol disodium group, fospropofol disodium (10-12.5 mg/kg) is intravenously injected. After the patient's Modified Observer's Assessment of Alertness/Sedation (MOAA/S) s
Propofol group:Anesthesia induction:In the propofol group, propofol (1.5-2 mg/kg) is intravenously injected.Anesthesia maintenance:In the propofol group, propofol is continuously pumped at an initial
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1.Age between 18 and 80 years old 2.Scheduled for laparoscopic resection of hepatocellular carcinoma (HCC) 3.ASA I-III
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1.Preoperative ALT/AST > 3 times the normal value 2.History of lipid metabolism disorders (e.g., familial hyperlipidemia) 3.Allergy to propofol or fospropofol 4.Child-Pugh class C
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver Function(ALT/AST); | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver Function(ALT/AST);Perioperative lipid metabolism indices (TG/TC/LDL-C/HDL-C);Anesthesia recovery time, orientation recovery time;Length of hospital stay, incidence of postoperative 30-day complications; | — |
Countries
China
Contacts
Public ContactCheng Yun
Zhejiang Cancer Hospital
Outcome results
None listed