Allergic rhinitis
Conditions
Interventions
Observation group:NA
Sponsors
Shanghai Tongji Hospital (Tongji Hospital of Tongji University)
Eligibility
Sex/Gender
All
Age
5 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for allergic rhinitis; 2. Age between 5 and 60 years; 3. Patients fully understand the advantages of allergen-specific immunotherapy, potential risks, and corresponding countermeasures, and voluntarily choose and accept allergen-specific immunotherapy; 4. For patients with comorbid asthma, asthma must be stable after treatment, with no exacerbations in the past 2 months and normal pulmonary function test results; 5. Provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. The patient is unable to fully understand the risks of allergen-specific immunotherapy; 2. Accompanied by severe or uncontrolled asthma (FEV1 < 80% of predicted value) and irreversible obstructive airway diseases; 3. Patients currently using beta-blockers or angiotensin-converting enzyme (ACE) inhibitors; 4. Severe cardiovascular diseases, immune disorders, mental or psychological illnesses, malignant tumors, etc.; 5. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Allergic Rhinitis Symptom Score (VAS) ;Allergic Rhinitis Symptom Score (TNSS) ; Combined Symptom and Medication Score (CSMS) ; Rhinoconjunctivitis Quality of Life (RQLQ); | — |
Secondary
| Measure | Time frame |
|---|---|
| specific IgE;specific IgG;Th1 cell;Th2 cell;Th17 cell;Treg cell; | — |
Countries
China
Contacts
Public ContactYu Shaoqing
Shanghai Tongji Hospital (Tongji Hospital of Tongji University)
Outcome results
None listed