Circulatory failure
Conditions
Interventions
Observation Group:None
Sponsors
Peking Union Medical College Hospital,Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult patients (aged >=18 years) 2. Admitted to the emergency room due to circulatory failure (definition of circulatory failure): (1) Major circulatory disorder: mean arterial pressure (MAP) 100 beats per minute. (2) Microcirculation disorders: skin mottles, prolonged capillary refill time, oliguria or hyperlactatemia. (3) Therapeutic intervention requirements: Fluid resuscitation, vasopressors or positive inotropic drugs are needed for support. 3. Time window: Within 24 hours of entering the emergency room
Exclusion criteria
Exclusion criteria: 1. pregnant woman; 2. DNR; 3. Confounding factors such as dark skin tone, cutaneous lesions, and traumatic injuries may compromise the accuracy of CRT;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between CRT and POP-derived parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation in subgroup analysis (sepsis subgroup and hyperlactatemia subgroup);Comparison of microcirculatory parameters between subgroups (difference in POP-derived parameters between finger CRT >=3 seconds and CRT <3 seconds groups);Prediction of 28-day mortality (CRT and POP-derived parameters);Predictive value of the difference and dynamic changes in finger-to-toe CRT and POP-derived parameters for 28-day mortality; | — |
Countries
China
Contacts
Public ContactXu Jun
Peking Union Medical College Hospital,Chinese Academy of Medical Sciences
Outcome results
None listed