Melasma
Conditions
Interventions
Observation group:None
Sponsors
The Affiliated Hospital of Chengde Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18 years old <= age <= 75 years old, no gender restriction; 2. Meet the above Western medical diagnostic criteria for chloasma and/or facial wrinkles; 3. Plan to use silkworm cocoon powder externally in real diagnosis and treatment scenarios and can adhere to the use; 4. Have basic communication and cognitive abilities, and can cooperate in completing basic efficacy evaluation and safety records; 5. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with allergy or intolerance to the active ingredients or excipients (contraindicated as clearly stated in the product instructions); 2. Pregnant or lactating women, or those planning a pregnancy in the near future (risk noted in the product instructions); 3. Individuals with concurrent active skin lesions, or a history of ochronosis or Cushing's syndrome; 4. Individuals who have used other depigmenting agents, systemic glucocorticoids, or photosensitizing drugs within the past 1 month; 5. Individuals unable to comply with sun protection measures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MASI/mMASI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Local skin adverse events; | — |
Countries
China
Contacts
Public ContactJiang Song
The Affiliated Hospital of Chengde Medical University
Outcome results
None listed