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Study on the efficacy and safety of esmketamine in MECT treatment of depression in adolescents with suicidal ideation or self injurious behavior

Study on the efficacy and safety of esmketamine in MECT treatment of depression in adolescents with suicidal ideation or self injurious behavior

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123127
Enrollment
Unknown
Registered
2026-04-22
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

control group:Received antidepressants+6 times of conventional MECT (propofol anesthesia)
Test group:Received antidepressant drugs+6 times of MECT treatment (anesthesia with esketamine combined with propofol at the first treatment, the dose was 0.25mg/kg)

Sponsors

Ya'an Fourth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 19 Years

Inclusion criteria

Inclusion criteria: 1. The patients' age ranged from 12 to 19 years old, and their condition met the diagnostic criteria of major depressive disorder in dsm-5. 2. Accompanied by serious suicidal ideation; 3. There are indications for MECT treatment (according to the expert consensus on electroconvulsive therapy (2017 version)); 4. Able to cooperate with questionnaire survey; 5. The study was approved by myself, family members or legal guardians, and the informed consent was signed.

Exclusion criteria

Exclusion criteria: 1. Suffering from brain organic diseases, cardiovascular diseases, diabetes, thyroid diseases, tumors and other serious physical diseases; 2. Subjects who could not receive MECT treatment.

Design outcomes

Primary

MeasureTime frame
Center for Epidemiologic Studies Depression Scale for Children;Beck Scale for Suicide Ideation;

Countries

China

Contacts

Public ContactXu Liuxiu

Ya'an Fourth People's Hospital

bingmayone@qq.com+86 158 8123 4513

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026