Diabetes mellitus, age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, primary angle-closure glaucoma, cataract, Alzheimer disease, Parkinson disease
Conditions
Interventions
Primary angle-closure glaucoma observation group:None
Group of patients with diabetes without ocular complications:None
Healthy control group:None
Parkinson's disease observation group:None
Age-related macular degeneration observation group:None
Retinal vein occlusion observation group:None
Diabetic retinopathy observation group:None
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old. 2. Voluntarily participate in this study, understand and sign the written informed consent form, and be able and willing to cooperate to complete the examinations. 3. Diagnosed by a specialist with at least one of the following eye diseases: AMD, DR, RVO, PACG, cataract, AD, PD, or a diabetic patient without ocular complications, or in a relatively healthy state without the target disease signs.
Exclusion criteria
Exclusion criteria: 1. The study eye has active infection, inflammation, trauma or a history of eye surgery. 2. The study eye has recently undergone intraocular surgery (such as cataract surgery) or intraocular procedures (such as laser treatment, intravitreal injection, etc.), or is using systemic drugs that may interfere with metabolism (such as systemic hormones, immunosuppressants, etc.). 3. Has severe and uncontrolled systemic diseases other than the target disease (such as autoimmune diseases, malignant tumors, liver and kidney failure, hyperthyroidism, etc.). 4. Is using local eye drops that may significantly affect the components of tear secretion. 5. Regularly wears contact lenses, OK lenses, etc. 6. Has any cognitive or physical disorder that affects the collection of tear samples or the cooperation in the examination. 7. Pregnant or lactating women. 8. The investigator determines that there are any other circumstances that make participation in this study inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear metabolite/lipid profile; | — |
Countries
China
Contacts
Public ContactKun Liu
Shanghai General Hospital
Outcome results
None listed