sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1: Age >18 years; 2: The definition of sepsis should be referred to the sepsis guidelines of 2016, and the initial arterial blood lactate should be >=4mmol/ when the sepsis patient was admitted into ICU department
Exclusion criteria
Exclusion criteria: 1. After ICU admission, patients with normal plasma lactate level, and the hospitalization time of the patient was less than 72 hours; 2. Patients who received high doses of catecholamines before ICU admission; 3. Patients with medical history of cirrhosis or hepatic insufficiency; 4. Patients had medical history of chronic renal insufficiency, and a serum endogenous creatinine clearance rate (Ccr) of 50%; 5. Patients who were diagnosed as diabetic and treated with metformin; 6. Patients diagnosed with lymphoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lactate clearance rate;Mortality; | — |
Countries
China
Contacts
The First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine