Epilepsy
Conditions
Interventions
Epilepsy with Comorbid Headache Patients Cohort:None
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
14 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=14 years; 2.Epilepsy patients meeting ILAE diagnostic criteria, classified according to ICD-10 codes as focal onset (G40.0~G40.2), generalized onset (G40.3G~40.5), or unknown onset (G40.6~G40.8); 3.Comorbid primary headache meeting ICHD-3 criteria, or epilepsy-related headache; 4.Signed informed consent;
Exclusion criteria
Exclusion criteria: 1.Severe psychiatric disorders (meeting DSM-V diagnostic criteria); 2.Severe organic diseases (such as malignant tumors) with expected survival time <1 year; 3.Diseases that can cause secondary headaches such as head trauma, brain tumors, cerebrovascular diseases; 4.History of substance dependence or abuse; 5.Unable to complete follow-up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of Headache Treatment Status in Epilepsy Patients with Comorbid Headache; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Headache Frequency and Severity after Different Treatments;Changes in Quality of Life after Different Treatments;Changes in Seizure Frequency after Different Treatments;Incidence of Treatment-related Adverse Reactions;Genomic Analysis in Different Headache Types;Clinical Characteristics and Patterns of Different Types of Epilepsy with Comorbid Headache;Proportion of Different Headache Types in Epilepsy Patients;Blood Biomarker Levels in Different Headache Types; | — |
Countries
China
Contacts
Public ContactXu Huiqin
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed