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Impact of postpartum infection on bronchopulmonary dysplasia and pulmonary hypertension in preterm infants

Impact of postpartum infection on bronchopulmonary dysplasia and pulmonary hypertension in preterm infants: A retrospective cohort study based on 244 preterm infants

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123085
Enrollment
Unknown
Registered
2026-04-21
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchopulmonary dysplasia(BPD) and its severe and life-threatening complications include BPD-related pulmonary vascular disease (PVD) and pulmonary hypertension (PH).Postpartum infection (sepsis)

Interventions

Preterm infants non-BPD group:None
Preterm infant BPD group:None

Sponsors

Army Medical Center of PLA
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Preterm infants with a gestational age of less than 32 weeks; 2. Born in the NICU of the Army Specialty Medical Center from January 2015 to December 2025; 3. No loss to follow-up, no missing key data, survived until discharge, and completed BPD and PH related diagnostic and treatment evaluations.

Exclusion criteria

Exclusion criteria: 1. Individuals with more than 30% missing key baseline data (gender, birth weight, gestational age); 2. Individuals missing BPD severity grading or PH status (only applicable to the subgroup analysis cohort); 3. Individuals who abandoned treatment or died within 3 days of hospitalization due to severe infection, shock, or other reasons; 4. Individuals diagnosed with genetic metabolic diseases or severe cardiopulmonary malformations (such as congenital heart disease, diaphragmatic hernia).

Design outcomes

Primary

MeasureTime frame
Diagnosis and severity grading of BPD;Diagnosis of pulmonary hypertension (PH);Diagnosis of postpartum sepsis;

Countries

China

Contacts

Public ContactZhangxue Hu

Army Medical Center of PLA

huzx1@163.com+86 23 6872 9137

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026