FindTrial
Sign In

Prediction of Esophageal and Gastric Varices in Liver Cirrhosis via Multimodal Ultrasound Combined with Radiomics and Laboratory Indicators: Development and Validation of a Machine Learning Model

Prediction of Esophageal and Gastric Varices in Liver Cirrhosis via Multimodal Ultrasound Combined with Radiomics and Laboratory Indicators: Development and Validation of a Machine Learning Model

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123077
Enrollment
Unknown
Registered
2026-04-21
Start date
2026-04-22
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophagogastric varices in liver cirrhosis

Interventions

Liver cirrhosis without esophageal and gastric varices group:None
Liver cirrhosis with esophageal and gastric varices group:None

Sponsors

The First Affiliated Hospital of the Baotou Medical College of Inner Mongolia University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 68 Years

Inclusion criteria

Inclusion criteria: 1. Age: Patients aged >= 18 years. 2. Diagnosis: Met the diagnostic criteria for liver cirrhosis as outlined in the Guidelines for the Diagnosis and Treatment of Liver Cirrhosis. 3. Procedure: Underwent gastroscopy. 4. Data & Consent: Complete clinical data and signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Comorbidities: Complicated with malignancy, liver failure, myelodysplastic syndrome, hematological disorders, or autoimmune diseases. 2. Treatment History: History of interventional therapy for portal hypertension. 3. Etiology: Portal hypertension not caused by liver cirrhosis. 4. Physiological Status: Pregnant or lactating women. 5. Cooperation: Unable to cooperate with the ultrasound examination (e.g., inability to hold breath due to dyspnea). 6. Data Quality: Incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
General Information (age, gender, etiology of liver cirrhosis, medical history);Multimodal Ultrasound Indexes (liver two-dimensional morphology, liver stiffness index, inner diameter of portal vein, portal vein flow velocity, spleen size (longitudinal diameter, thickness), spleen;Endoscopic Examination;Model Evaluation Indicators;Laboratory parameters: Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Total bilirubin (TBil), Direct bilirubin (DBil), Platelet count (PLT), Serum albumin (ALB), Prothrombin time (P;radiomics feature extraction;—

Countries

China

Contacts

Public ContactWang Fengyun

The First Affiliated Hospital of the Baotou Medical College of Inner Mongolia University of Science and Technology

2276306545@qq.com+86 472 2178075

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026