FindTrial
Sign In

Effect of Low-Frequency Rhythmic Auditory Stimulation on Emergence Agitation in Children Undergoing Tonsillectomy and Adenoidectomy: A Randomized Controlled Trial

Effect of Low-Frequency Rhythmic Auditory Stimulation on Emergence Agitation in Children Undergoing Tonsillectomy and Adenoidectomy: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123073
Enrollment
Unknown
Registered
2026-04-21
Start date
2026-04-30
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillar hypertrophy with adenoid hypertrophy

Interventions

Control group:non-rhythmic white noise were played
Intervention group:A soft rhythmic sound at 0.1 Hz (˜6 cycles/min)

Sponsors

Foshan Women and Children Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. 3-7 years old; 2. ASA I-II; 3. Elective tonsil and adenoid removal surgery; 4. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Hearing impairment; 2.Congenital heart disease; 3.Neurodevelopmental disorders; 4.Intraoperative use of dexmedetomidine; 5.Incomplete ECG recording; 6.Surgery duration exceeding 60 minutes.

Design outcomes

Primary

MeasureTime frame
ncidence of non-pain-related emergence agitation (PAED score >= 10 and FLACC score <= 3);—

Secondary

MeasureTime frame
Severity of emergence agitation (PAED score);Extubation time and PACU length of stay;Postoperative pain score (FLACC scale);Heart rate variability parameters (SDNN, RMSSD, LF/HF ratio);Incidence of adverse events;—

Countries

China

Contacts

Public ContactZhang Xinyue

Foshan Women and Children Hospital

zxyhxq@yeah.net+86 7570000000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026