HIV
Conditions
Interventions
Control Group:Routine outpatient follow-up, monitoring HIV viral load, CD4 count, and basic metabolic indicators (such as fasting blood glucose, blood pressure, etc.) every 3 months, and managing abno
TCMP Group:1. Target value setting and dynamic management:
(1) Five core metabolic targets: BMI (=2 items not met or medium-risk: Initiate drug intensification (such as adding metformin, statins),
Observation group (Cross-section):None
Sponsors
Chongqing Public Health Medical Treatment Center
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=50 years old; 2. HIV-infected individuals (diagnosed in accordance with the "Chinese AIDS Diagnosis and Treatment Guidelines (2024 Edition)"); 3. CD4+ >=200 cells/mm^3; 4. No concurrent chronic physical diseases (as per the "Expert Consensus on Coexistence of Multiple Diseases in the Elderly (2022)").
Exclusion criteria
Exclusion criteria: 1. Concurrent active opportunistic infections, including but not limited to: CMV infection, cryptococcal infection, AIDS-related tumors, tuberculosis, hepatitis B, hepatitis C, etc. 2. Active cancer was present within 12 months prior to entering the study. 3. Specific immunosuppressants or immunomodulators, including but not limited to tacrolimus, sirolimus, rapamycin, mycophenolate mofetil, cyclosporine, TNF-a blockers or antagonists, azathioprine, interferon, growth factors or intravenous immunoglobulin (IVIG), should be used within 30 days prior to the start of the study. 4. Currently, erythromycin, colchicine or rifampicin are being used. 5. Known active or recent (not completely cured within 30 days before enrollment) systemic bacterial, fungal, parasitic or viral infections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Monitoring of metabolism-related indicators;Monitoring of aging indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Verification of comorbidity status; | — |
Countries
China
Contacts
Public ContactHuan Li
Chongqing Public Health Medical Center,
Outcome results
None listed