Sarcopenia
Conditions
Interventions
Gold Standard:dual energy X-ray absorptiometry,DXA
Index test:Measure the fiber length and thickness of the vastus lateralis and medial head of the gastrocnemius muscles using ultrasound and calculate the ultrasound sarcopenia index of both.
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 50 years; 2.Clear history of chronic musculoskeletal pain of more than 3 months duration; 3.BMI 20-30 kg/m^2; 4.Willingness and ability to comply with the protocol.
Exclusion criteria
Exclusion criteria: 1.Recent barium or contrast-enhanced tests done; 2.Neurologic diseases with mobility impairment; 3.Dementia or moderate-severe cognitive impairment identified by score <24 of Mini-Mental State Examination Test (MMSE), according to Folstein et al. 4.Severe cardiopulmonary diseases; 5.Cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle thickness of vastus lateralis;Fascicle length of Medial gastrocnemius muscle;Muscle thickness of Medial gastrocnemius muscle;Muscle mass;Fascicle length of vastus lateralis;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gait speed test;Grip strength;receiver operating characteristic curve,ROC; | — |
Countries
China
Contacts
Public ContactShaoling Wu
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed