Breast Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Female, age >= 45 years; 2. Diagnosed with invasive breast cancer according to the "Breast Cancer Diagnosis and Treatment Guidelines" (2022 edition); 3. Receiving adjuvant chemotherapy or neoadjuvant chemotherapy for the first time with therapeutic intent; 4. Patient is conscious and able to communicate in writing and verbally; 5. Expected survival >= 1 year.
Exclusion criteria
Exclusion criteria: 1.Definite history of stroke, Parkinson's disease, epilepsy, multiple sclerosis, severe traumatic brain injury, or any other known neurological disorder that may cause cognitive impairment. 2.Complicated with brain tumor or brain metastasis; history of intracranial radiotherapy, prior radiotherapy/chemotherapy, or brain surgery/trauma. 3.Presence of severe frailty (e.g., FRAIL scale score >=4) or diagnosed dementia / moderate-to-severe cognitive impairment (MoCA <26 for preliminary screening) at baseline assessment (T0). 4.Receiving psychopharmacological and/or psychological treatment. 5.Presence of visual, hearing, speech, or limb function abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frailty;Cognitive ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Social Support;Depression;Anxiety;Self-management efficacy;Activity;Sleep Quality;Nutritional Status; | — |
Countries
China
Contacts
The Second Norman Bethune Hospital of Jilin University