Postoperative delirium
Conditions
Interventions
Sponsors
The First People's Hospital of Changde City
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age greater than or equal to 65 years old 2. Undergoing elective hip/knee joint replacement surgery under combined spinal-epidural anesthesia 3. Weight range 50 to 80 kg 4. ASA classification II-III 5. Prior to the operation, cognitive function was intact and the patient had the educational background to complete the preoperative neuropsychological tests.
Exclusion criteria
Exclusion criteria: 1.Mini-Mental State Examination (MMSE) score <= 24; 2.Severe mental disorders and severe systemic diseases; 3.Coagulation dysfunction; 4.Central nervous system infection, head trauma, epilepsy, neurological diseases, etc.; 5.Missing data and postoperative loss to follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preoperative and intraoperative bilateral electroencephalogram waveforms and raw data;Common vital signs of the patient during the operation;The incidence of postoperative delirium;The potential relationship between the immunometabolic chemical substances in patients with postoperative delirium and their brain electrical waves;The incidence rates of postoperative nausea and vomiting (PONV) and other complications (postoperative infection, deep vein thrombosis);Immunometabolic analysis of cerebrospinal fluid in patients with postoperative delirium; | — |
Countries
China
Contacts
Public ContactHuajing Guo
The First People's Hospital of Changde City
Outcome results
None listed