Severe Upper Limb Hemiplegia After Stroke
Conditions
Interventions
Ipsilateral Cortex Inhibition Group:Continuous Theta Burst Stimulation (cTBS) for Inhibiting the Ipsilateral Cortex
Ipsilateral Cortex Excitation Group:Intermittent Theta Burst Stimulation (iTBS) for Exciting the Ipsilateral Cortex
Standard Control Group:routine rehabilitation
Sponsors
Fuxing Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis meets the key diagnostic points for various cerebrovascular diseases passed at the 1995 National Fourth Cerebrovascular Disease Academic Conference, and subcortical stroke is confirmed by CT or MRI; 2. First onset and unilateral occurrence, with stable condition; 3. Disease duration between 2 weeks and 6 months; age between 18 and 80 years; 4. Accompanied by severe upper limb motor dysfunction, and Brunnstrom stage 2-3 of the affected upper limb (at least partial active shoulder movement); 5. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Combined with obvious increased muscle tone in the affected upper limb (Ashworth grade = 2); 2. Combined with obvious joint contracture, shoulder-hand syndrome, shoulder pain, and other complications; 3. Combined with severe deep or superficial sensory impairment of the limbs; 4. Combined with severe cognitive impairments such as visuospatial neglect and tilt syndrome; 5. Combined with intracranial infection, multiple system atrophy, post-stroke depression, and other neuropsychiatric disorders; 6. Presence of metal implants in the body; 7. Claustrophobia; 8. History of epilepsy; 9. Other conditions deemed unsuitable for participation in this clinical study by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Behavioral effect;Brain Network Properties;Reorganized Motor Network; | — |
Countries
China
Contacts
Public ContactRan Li
Fuxing Hospital, Capital Medical University
Outcome results
None listed