Interstitial Lung Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Hospitalized patients aged 18-80 years, diagnosed with AE-ILD between January 1, 2021, and January 1, 2026. 2. Patients diagnosed with ILD according to the 2013 American Thoracic Society/European Respiratory Society (ATS/ERS) official statement, and concurrently meeting the AE-ILD diagnostic criteria extended from the 2016 ATS/ERS guidelines on acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF). 3. Cases were jointly determined as infectious or non-infectious by two attending physicians (or higher) from the Respiratory Department. 4. Possessing complete inpatient medical records, laboratory data, imaging data, and at least 180 days of follow-up information.
Exclusion criteria
Exclusion criteria: 1. Complicated with active malignant tumors, end-stage liver or kidney failure, primary immunodeficiency diseases, HIV infection, or post-organ transplant status. 2. Pregnant or breastfeeding women. 3. Acute respiratory failure caused by other triggers such as trauma, pneumothorax, pulmonary embolism, or heart failure. 4. Severe lack of clinical data, where key differential indicators (e.g., chest imaging, etiological results) are unavailable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Outcomes;Area under the ROC curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Etiological indicators;Laboratory indicators;Symptomatology;Pulmonary function; | — |
Countries
China
Contacts
Nanjing Drum Tower Hospital