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Effect of Remimazolam on Intraoperative Respiratory Depression in Patients Undergoing Tubeless VATS

Effect of Remimazolam on Intraoperative Respiratory Depression in Patients Undergoing Tubeless VATS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123014
Enrollment
Unknown
Registered
2026-04-21
Start date
2026-04-21
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Remimazolam Besylate Group:Remimazolam Besylate Group

Sponsors

Deyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for elective Tubeless VATS procedures; 2.Aged 18-60 years; 3.Eastern Cooperative Oncology Group (ECOG) performance status score of <=1; 4.American Society of Anesthesiologists (ASA) physical status classification of Class ? or below; 5.The patient and/or their legally authorized representative has provided written informed consent and voluntarily agreed to participate in the study prior to any study-related procedures.

Exclusion criteria

Exclusion criteria: 1.Preoperative examinations indicate extensive pleural adhesions or a history of prior thoracic surgery and/or radiotherapy; 2.Patients with preexisting severe cardiopulmonary dysfunction that would preclude safe tolerance of the surgical procedure; 3.Dementia, epilepsy, or other active neurological disorders (e.g., cerebrovascular disease, neurodegenerative diseases, or conditions with significant cognitive impairment); 4.Contraindications to regional nerve blockade (e.g., local infection at puncture site, coagulopathy, or patient refusal); 5.Coagulation disorders ; 6.High risk of aspiration (e.g., gastroesophageal reflux disease, hiatal hernia, or uncontrolled gastric contents); 7.Body mass index (BMI) >28 kg/m^2; 8.Airway abnormalities or anticipated difficult airway (Mallampati classification =III, thyromental distance <6 cm); 9.Other conditions deemed by the investigator to be unsuitable for study participation.

Design outcomes

Primary

MeasureTime frame
Occurrence of intraoperative respiratory depression events requiring airway intervention;

Secondary

MeasureTime frame
Postoperative Pulmonary Complications;NASA Task Load Index;Periprocedural time parameters and hospitalization costs;Arterial blood gas analysis results;Intraoperative Adverse Events;Hemodynamic parameters, including heart rate (HR), blood pressure (BP), mean arterial pressure (MAP), and others.;Respiratory Parameters;

Countries

China

Contacts

Public ContactJia Han

Deyang People's Hospital

453922152@qq.com+86 838 2418184

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026