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Study on the efficacy of propolis suppository in treating functional constipation and its effects on intestinal flora

Study on the efficacy of propolis suppository in treating functional constipation and its effects on intestinal flora

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123001
Enrollment
Unknown
Registered
2026-04-20
Start date
2026-04-20
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional constipation is characterized by difficult defecation, fewer than 3 bowel movements per week, or incomplete emptying, without organic lesions, and the of the disease is usually more than 6 months.

Interventions

control group:Enema
Treatment group:honey

Sponsors

The Third Affiliated Hospital of Zhejiang Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 78 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of functional constipation in western medicine and the syndrome differentiation criteria of traditional Chinese medicine; 2. Age 20-78 years; 3. No use of antibiotics and probiotics within 1 month; 4. Informed consent of patients and signing of informed consent forms;

Exclusion criteria

Exclusion criteria: 1. Complicated with organ diseases and systemic diseases related to FC; 2. Diseases with severe hematopoietic system, nerve and cardiovascular damage; 3. Pregnant, lactating women; 4. History of gastrointestinal surgery;

Design outcomes

Primary

MeasureTime frame
Microbial community detection and analysis;The main symptom scores of constipation were assessed;

Secondary

MeasureTime frame
Inflammatory markers;

Countries

China

Contacts

Public ContactChen Zhongming

The Third Affiliated Hospital of Zhejiang Chinese Medical University

czm.87@163.com+86 571 8837 4908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026