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A randomized controlled trial of oropharyngeal muscle training combined with UPPP in the treatment of moderate to severe OSAHS

A randomized controlled trial and efficacy prediction study of tongue muscle biofeedback-guided oropharyngeal muscle training combined with UPPP surgery for moderate to severe OSAHS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122971
Enrollment
Unknown
Registered
2026-04-20
Start date
2026-04-22
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moderate to severe obstructive sleep apnea hypopnea syndrome (OSAHS)

Interventions

Control group:Uvulopalatopharyngoplasty
Experimental group:Uvulopalatopharyngoplasty plus tongue biofeedback–guided oropharyngeal myofunctional training

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age 18–65 years; 2.Retropalatal narrowing; 3.Willingness to undergo UPPP; 4.Moderate-to-severe OSAHS confirmed by PSG or type II/III home sleep testing (AHI >=15 events/hour); 5.Written informed consent provided;

Exclusion criteria

Exclusion criteria: 1.Patients with deviated nasal septum and chronic sinusitis; 2.Severe systemic diseases or conditions contraindicating surgery/training (e.g., coagulopathy, immune disorders, asthma, malignancy, chronic heart failure); 3.Acute illness within the past 2 weeks (e.g., URI, fever);

Design outcomes

Primary

MeasureTime frame
Treatment effectiveness rate;—

Secondary

MeasureTime frame
Nadir peripheral capillary oxygen saturation(Nadir SpO2);The Epworth Sleepiness Scale;Evaluation of surgical-related adverse events;Oxygen desaturation time percentage (CT90);Mean blood oxygen saturation (Mean SpO2);Pittsburgh Sleep Quality Index;Evaluation of adverse events related to oropharyngeal muscle training;—

Countries

China

Contacts

Public ContactShen Hong

Peking University First Hospital

shen_ent@163.com+86 10 56957831

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026