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Perioperative Changes and Outcomes of Filtering Bleb Internal Structure after Trabeculectomy in Glaucoma Patients Based on AS-OCT and Histological Examination

Perioperative Changes and Outcomes of Filtering Bleb Internal Structure after Trabeculectomy in Glaucoma Patients Based on AS-OCT and Histological Examination

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122954
Enrollment
Unknown
Registered
2026-04-20
Start date
2026-04-20
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

Post-Trabeculectomy:None

Sponsors

The Zhongshan Ophthalmic Center,Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with glaucoma and requiring trabeculectomy; 2.Age >= 18 years; 3.Patients who consent to postoperative follow-up and are capable of cooperating with imaging examinations.

Exclusion criteria

Exclusion criteria: 1.Previous history of relevant ocular surgeries, such as vitrectomy or ab-externo procedures; 2.Coexisting ocular conditions, including ocular surface inflammation, severe dry eye, or intraocular tumors; 3.Severe systemic diseases; 4.Insufficient follow-up duration or missing data.

Design outcomes

Primary

MeasureTime frame
Bleb fluid index(BFI);Intraocular pressure;—

Secondary

MeasureTime frame
Bleb cavity height(BCH);Striped phenomenon(SP);Total bleb height(TBH);Bleb cavity edge angle(BCEA);Cysts;Bleb wall thickness(BWT);—

Countries

China

Contacts

Public ContactMingkai Lin

The Zhongshan Ophthalmic Center,Sun Yat-sen University

linmingkai@gzzoc.com+86 20 66615460

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026