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To investigate the prediction and risk factors of acute respiratory distress syndrome (ARDS) after cardiopulmonary bypass (CPB) based on lung ischemia-reperfusion multi-omics sequencing data

To investigate the prediction and risk factors of acute respiratory distress syndrome (ARDS) after cardiopulmonary bypass (CPB) based on lung ischemia-reperfusion multi-omics sequencing data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122929
Enrollment
Unknown
Registered
2026-04-20
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome (ARDS)

Interventions

Gold Standard:The gold standard for diagnosing acute respiratory distress syndrome (ARDS) following cardiopulmonary bypass (CPB) is the comprehensive clinical and physiological diagnostic criteria out
Index test:Multi-Omics Detection and Analytical Technology Portfolio

Sponsors

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Scheduled for elective cardiac surgery with cardiopulmonary bypass at our hospital, meeting the diagnostic criteria and surgical indications for coronary atherosclerotic heart disease or valvular heart disease as specified in the Clinical Diagnosis and Treatment Guidelines (Cardiovascular Surgery Volume); 2.Patient age between 35 and 80 years; 3.Good patient compliance, with signed informed consent obtained.

Exclusion criteria

Exclusion criteria: 1.Patients undergoing surgery not meeting standard cardiac surgical indications but operated for other reasons; 2.Patients with a history of chronic pulmonary diseases (e.g., COPD, asthma), pleural effusion or atelectasis, previous cardiopulmonary bypass surgery, autoimmune diseases (e.g., systemic lupus erythematosus, Sjögren's syndrome), or concurrent malignancies.

Design outcomes

Primary

MeasureTime frame
Postoperative Onset of Acute Respiratory Distress Syndrome;

Countries

China

Contacts

Public ContactLu Peng

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)

penglu@njmu.edu.cn+86 25 68303105

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026