acute respiratory distress syndrome
Conditions
Interventions
the prolonged prone positioning ventilation (PPP) group:none
standard prone positioning ventilation (SPP) group:none
Sponsors
Chongqing University Affiliated Shapingba Hospital (Shapingba District People's Hospital of Chongqing)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: In accordance with the Berlin diagnostic criteria proposed by the 2011 ARDS Definition Task Force, with P/F = 150 mmHg and positive end-expiratory pressure (PEEP) = 5 cmH2O (1 cmH2O = 0.098 kPa); an artificial airway is established through tracheostomy or endotracheal intubation, and the patient receives continuous invasive mechanical ventilation support.
Exclusion criteria
Exclusion criteria: 1. Age <18 years; 2. Unresolved intracranial hypertension; 3. Unstable spinal cord injury or fracture requiring restricted positioning; 4. Severe burns and head/face injuries; 5. Chest or abdominal surgical incisions or trauma that have not healed; 6. Severe hemodynamic instability; 7. Acute hemorrhagic diseases; 8. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICU mortality after initiating prone ventilation; | — |
Secondary
| Measure | Time frame |
|---|---|
| the occurrence of pressure injuries on anterior body surfaces;ventilator liberation;ICU discharge;prone-related complications;Changes in oxygenation and respiratory mechanics; | — |
Countries
China
Contacts
Public ContactZheng Aihua
Chongqing University Affiliated Shapingba Hospital (Shapingba District People's Hospital of Chongqing)
Outcome results
None listed