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Cancelled by the investigator. The Value of Multimodal Circulatory Monitoring in Guiding Decoupled Treatment for Sepsis-Induced Shock Resuscitation

The Value of Multimodal Circulatory Monitoring in Guiding Decoupled Treatment for Sepsis-Induced Shock Resuscitation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122911
Enrollment
Unknown
Registered
2026-04-20
Start date
2023-05-01
Completion date
Unknown
Last updated
2026-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic shock

Interventions

Group A:Cv-aCO2/Ca-vO2=6mmHg:None
Group C:Cv-aCO2/Ca-vO2>1Pv-aCO21Pv-aCO2>=6mmHg:None

Sponsors

The Third People’s Hospital of Chengdu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Aged >= 18 years old and = 8 mmHg after adequate resuscitation, requiring norepinephrine (>= 0.02 µg/kg/min) to maintain mean arterial pressure (MAP) >= 65 mmHg, and blood lactate > 2 mmol/L.

Exclusion criteria

Exclusion criteria: 1. Pregnant women; 2. Patients complicated with severe chronic obstructive pulmonary disease (COPD); 3. Patients with restricted treatment efforts; 4. Patients with a history of sepsis or septic shock within the previous 3 months; 5. Patients complicated with malignant tumors; 6. Patients complicated with severe liver cirrhosis (Child-Pugh Class C).

Design outcomes

Primary

MeasureTime frame
Arterial and Venous Blood Gas Analysis at 6 Hours Post ICU Admission;Sublingual Microcirculation at 6 Hours Post ICU Admission;—

Secondary

MeasureTime frame
Duration of endotracheal intubation;—

Countries

China

Contacts

Public ContactChuanliang Pan

The Third People’s Hospital of Chengdu

cl.pan@foxmail.com+86 181 1158 6553

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026