None
Conditions
Interventions
S group:5 µg of sufentanil (diluted with normal saline to a total volume of 5 ml) was slowly injected via epidural needle.
N group:5ml of normal saline was injected via epidural needle.
Sponsors
Yichun Maternal and Child Health Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Full-term singleton pregnancies (>=37 weeks) 2. Natural childbirth 3. Cervical dilation 2–4 cm 4. ASA II 5. Voluntary acceptance of labor analgesia 6. Clear understanding and voluntary participation in this study, with informed consent signed by the individual or their family.
Exclusion criteria
Exclusion criteria: 1. Opioid allergy 2. Contraindication to spinal anesthesia 3. History of chronic pain or opioid use 4. Severe obstetric complications (gestational diabetes, gestational hypertension, gestational heart disease, etc.) 5. Participation in other drug clinical trials as a subject within the past 3 months; 6. Patients deemed unsuitable for this trial by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score-time area under the curve (AUC0-20) at 2 min (T2), 4 min (T4), 6 min (T6), 8 min (T8), 10 min (T10), 12 min (T12), 15 min (T15), and 20 min (T20) after T0.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in mean arterial pressure (MAP), heart rate (HR), and sedation score at time points T0, T5, T10, T15, and T20.;Analgesic onset time: defined as the time from T0 until the VAS score first becomes =3.; | — |
Countries
China
Contacts
Public ContactShen Haitao
Yichun Maternal and Child Health Hospital
Outcome results
None listed