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Neuroplasticity-Driven fNIRS Neurofeedback Training Enhances Corticomotor Coupling and Brain-Hand Interaction Efficiency in Post-Stroke Hemiparesis

Neuroplasticity-Driven fNIRS Neurofeedback Training Enhances Corticomotor Coupling and Brain-Hand Interaction Efficiency in Post-Stroke Hemiparesis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122898
Enrollment
Unknown
Registered
2026-04-20
Start date
2026-04-22
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke upper limb motor dysfunction

Interventions

Observation group II:fNIRS neurofeedback upper limb dual-task motor training
Observation group I:fNIRS neurofeedback upper limb active motor training
Control group:Passive upper limb motor training

Sponsors

Nanjing Zijin Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients in the subacute phase of stroke (2–4 weeks post-onset); 2.Presence of upper limb motor dysfunction (Fugl-Meyer Assessment–Upper Extremity score 24); 5.No severe spasticity or joint contracture affecting upper limb movement; 6.No contraindications for fNIRS or sEMG;

Exclusion criteria

Exclusion criteria: 1.History of other neurological disorders; 2.Severe psychiatric illness; 3.Inability to tolerate training intensity; 4.Participation in other interventional studies within the recent period;

Design outcomes

Primary

MeasureTime frame
FMA-UE;

Secondary

MeasureTime frame
HbO concentration, HbR concentration, ß-value, EMG amplitude, Barthel Index;

Countries

China

Contacts

Public ContactWang Xinwei

Nanjing Zijin Hospital

18851729275@163.com+86 25 8427 5767

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026