None
Conditions
Interventions
Remifentanil group:Remifentanil combined with propofol
Dizocine group:Dizocine combined with Propofol
Sponsors
Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years; 2. ASA (American Society of Anesthesiologists) physical status classification I-III; 3. Scheduled for elective painless gastroscopy and/or colonoscopy; 4. Signed written informed consent.
Exclusion criteria
Exclusion criteria: 1. Known allergy to the investigational drug; 2. Predicted difficult airway; 3. History of obstructive sleep apnea syndrome; 4. Severe cardiovascular or respiratory disease; 5. Severe hepatic or renal insufficiency; 6. Chronic use of sedatives or analgesics; 7. Pregnancy; 8. Body mass index (BMI) >30 kg/m² or <18 kg/m².
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity of intraoperative body movement reactions (grade 0-2); Endoscopist satisfaction (VAS 0-10);Total propofol consumption; Incidence of hypoxemia (SpO2 30%);Incidence of bradycardia (HR < 50 bpm);Postoperative pain (VAS at 30 and 60 minutes);Incidence of postoperative nausea and vomiting (PONV);Incidence of dizziness;Procedure time;Other adverse events; | — |
Countries
China
Contacts
Public ContactXiangsheng Xiong
Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)
Outcome results
None listed