Thyroid Surgery
Conditions
Interventions
Experimental group:30 minutes before the end of surgery, dexmedetomidine was administered intranasally at a dose of 2 µg/kg body weight.
Control Group:30 minutes before the end of the surgery, an equal volume of normal saline was administered intranasally
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Female patients undergoing primary thyroid surgery. 2. Aged 18–65 years, with ASA physical status I–III. 3. Normal communication ability. 4. Voluntarily signed informed consent. 5. BMI 18–30 kg/m².
Exclusion criteria
Exclusion criteria: 1. Patients who refuse to participate in the study. 2. Patients with a history of chronic pharyngitis or other chronic respiratory diseases. 3. Patients with a known allergy to the study drugs or a history of allergic constitution. 4. Patients who develop other postoperative complications. 5. Patients currently participating in other clinical trials. 6. Patients undergoing non-primary thyroid surgery or lateral cervical lymph node dissection. 7. Severe sinus bradycardia. 8. Severe nasal lesions or injuries. 9. Pregnant or lactating women. 10. Patients with an expected operative duration exceeding 3 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-operative sore throat severity;Incidence of POST-operative sore throat;Incidence and Severity Grading of Coughing During Tracheal Extubation ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of recovery-15 items; | — |
Countries
China
Contacts
Public ContactWu Min
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed