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Observation on the Efficacy of Labial Mucosa Graft in the Treatment of Eyelid Margin Keratinosis in Stevens-Johnson Syndrome

Observation on the Efficacy of Labial Mucosa Graft in the Treatment of Eyelid Margin Keratinosis in Stevens-Johnson Syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122884
Enrollment
Unknown
Registered
2026-04-20
Start date
2026-04-25
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stevens-Johnson Syndrome

Interventions

single group:We plan to enroll patients diagnosed with Stevens-Johnson syndrome accompanied by lid margin keratinosis, and perform eyelid margin keratectomy combined with labial mucosal grafting from

Sponsors

Xi'an No. 1 Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: SJS patients with lid margin keratinization.

Exclusion criteria

Exclusion criteria: 1. Eyes with total limbal stem cell deficiency, severe symblepharon, and complete ocular surface keratinization; 2. Patients complicated by ocular infection or other vision-threatening ocular complications, such as cataract, glaucoma, uveitis, or posterior segment abnormalities; 3. Patients with unstable systemic conditions; 4. Patients who were unable to comply with follow-up.

Design outcomes

Primary

MeasureTime frame
best corrected visual acuity;ocular surface severity score;—

Secondary

MeasureTime frame
corneal fluorescein staining score;—

Countries

China

Contacts

Public ContactYan Cheng

Xi'an No. 1 Hospital

haomi5292@163.com+86 29 8763 0848

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026