Alveolar bone defect
Conditions
Interventions
Control group:Pressure syringe injection of articaine injection solution
STA group:Injection of Articaine Injection using STA Painless Local Anesthesia Device
Celecoxib group:Oral administration of 0.4g celecoxib capsules before surgery, followed by injection of articaine injection using a pressure injector.
Experimental group:Oral administration of 0.4g celecoxib capsules before surgery, followed by injection of articaine injection using the STA painless local anesthesia device.
Sponsors
Hangzhou Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients classified as Class I or II according to the American Society of Anesthesiologists (ASA) classification; 2. Patients whose preoperative assessment indicates insufficient horizontal bone volume for direct implant placement, with approximately 3–4 mm of remaining horizontal bone volume, and who require guided horizontal bone regeneration; 3. Patients aged between 18 and 60 years; 4. Patients whose adjacent teeth in the surgical area are free of conditions such as pulpitis or apical periodontitis; 5. Patients who have not taken any analgesic medications within one week prior to surgery;
Exclusion criteria
Exclusion criteria: 1 .Individuals with severe and uncontrolled underlying diseases; 2 .those with a history of radiotherapy or chemotherapy within the past 5 years before surgery; 3. individuals with a history of allergy to celecoxib and non-steroidal anti-inflammatory drugs; 4. pregnant or breastfeeding women; 5. individuals with severe liver and kidney diseases and impaired liver and kidney function; 6. those taking bisphosphonates or antitumor drugs; 7. those requiring long-term use of analgesics or psychotropic drugs; 8. patients with uncontrolled periodontal disease;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale for Pain Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improved Dental Anxiety Scale Scoring;Number of oral painkillers taken within 48 hours post-surgery;Time of first pain medication administration within 48 hours post-surgery;Mean arterial pressure;Average heart rate; | — |
Countries
china
Contacts
Public ContactShi Hengrui
Hangzhou Traditional Chinese Medicine Hospital
Outcome results
None listed