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A Study on the Analgesic Effect of Liposomal Bupivacaine in Rhomboid-Intercostal-Serratus Anterior Plane Block for Postoperative Analgesia After Thoracoscopic Lobectomy

A Study on the Analgesic Effect of Liposomal Bupivacaine in Rhomboid-Intercostal-Serratus Anterior Plane Block for Postoperative Analgesia After Thoracoscopic Lobectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122868
Enrollment
Unknown
Registered
2026-04-20
Start date
2026-04-20
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Diseases

Interventions

Intervention Group:Perform rhomboid-intercostal-serratus anterior plane block with liposomal bupivacaine.
Control Group:Perform paravertebral block using liposomal bupivacaine.

Sponsors

Tangdu Hospital of the Fourth Military Medical University of the People's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for thoracoscopic partial pulmonary resection under general anesthesia, with an expected operative time of = 1 hour; 2.Aged >=18 years, with no gender restriction; 3.Body mass index (BMI) ranging from 18 to 30 kg/m^2; 4.American Society of Anesthesiologists (ASA) physical status classification Grade I–II; 5.Voluntarily signed informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with communication barriers or inability to cooperate with investigators, including communication or cognitive dysfunction that prevents understanding of the VAS scoring system, history of mental illness, epilepsy, Parkinson’s disease, myasthenia gravis, etc.; 2.Patients with known hypersensitivity to any study medications; 3.Patients with a history of chronic pain such as preoperative neuropathic pain; 4.Patients with confirmed or suspected history of alcohol, analgesic, or other drug abuse and addiction; 5.Patients who participated in other clinical trials within 3 months prior to study enrollment; 6.Patients considered by the attending physician or investigator to have other conditions unsuitable for participation in this study (reasons shall be documented).

Design outcomes

Primary

MeasureTime frame
Pain score;

Secondary

MeasureTime frame
The nerve block procedure time;Block-related complications;Perioperative hemodynamics;Intraoperative vasoactive drug usage;Incidence of intraoperative hypotension in the two groups;Postoperative pulmonary complications such as nausea, vomiting, and atelectasis;

Countries

China

Contacts

Public ContactChangjun Gao

Tangdu Hospital of the Fourth Military Medical University of the People's Liberation Army of China

gaocj74@163.com+86 29 8477 7439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026