Spinal cord injuries
Conditions
Interventions
Experimental Group:Epidural spinal cord stimulation
Sponsors
The Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 16 - 65 years old; 2. Spinal cord injury caused by trauma, with a duration of >= 6 months and = 1 level; 9. Percutaneous spinal cord electrical stimulation at the thoracic 12 and lumbar 1 segments can induce obvious electromyographic waveforms of lower limb muscle groups such as the biceps femoris, semitendinosus, gastrocnemius, and anterior tibialis; 10. Participants voluntarily participate in this study, sign the informed consent form, have good compliance, and cooperate with necessary postoperative rehabilitation training, examinations, and follow-up.
Exclusion criteria
Exclusion criteria: 1. Having a history of myocardial infarction or stroke within the past 6 months; 2. Diagnosed with mental disorders such as depression, with suicidal thoughts/risk; 3. Currently pregnant or planning to get pregnant during the study period; 4. Having a bleeding tendency or coagulation dysfunction (prothrombin time >= 18 seconds); 5. Having a history of alcohol or drug abuse or dependence; 6. Having intellectual disability, cognitive dysfunction or personality disorder; 7. Having other chronic diseases that may affect recovery (such as severe fractures, liver and kidney failure, severe anemia, etc.); 8. Implanted with a cardiac pacemaker, cardioverter defibrillator or defibrillator; 9. In addition to the above, there are other situations deemed inappropriate by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spinal Cord Injury Independence Scale;Spinal Cord Injury Walking Index Score (WISCI II);Adverse Events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Ashworth Scale;Functional Independence Scale;International Standard for Neurological Classification of Spinal Cord Injury;Penn Spasticity Frequency Scale;Pain VAS; | — |
Countries
China
Contacts
Public ContactJunming Zhu
The Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed