Skip to content

The effect of PAOO surgery on orthodontically induce external apical root resorption of anterior teeth in maxillary extraction cases - a retrospective study

The effect of PA00 surgery for orthodontic induced root resorption of maxillary anterior teeth -a retrospective study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122831
Enrollment
Unknown
Registered
2026-04-19
Start date
2025-06-24
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion orthodontically induced root resorption alveolar bone defect

Interventions

negtive control group:None
positive control group:Orthodontic treatment
experimental group:PAOO surgery and Orthodontic treatment

Sponsors

Stomatology Hospital,Zhejiang University School Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion Criteria for the Experimental Group (PAOO + Orthodontics Group): 1. Fixed orthodontic patients with an initial orthodontic age greater than 18 years, requiring the extraction of one premolar in each maxillary quadrant for space closure. 2. Underwent CBCT imaging before and after orthodontic treatment, and received PAOO surgery in the maxillary anterior region during orthodontic treatment. Inclusion Criteria for the Positive Control Group (Orthodontics Only Group): 1. Fixed orthodontic patients with an initial orthodontic age greater than 18 years, requiring the extraction of one premolar in each maxillary quadrant for space closure. 2. Underwent CBCT imaging before and after orthodontic treatment, but did not receive PAOO surgery during orthodontic treatment. 3. Showed no significant differences compared to the experimental group overall in terms of preoperative and postoperative crown and root movement distances, age, and orthodontic treatment duration. Inclusion Criteria for the Negative Control Group (Methodology Test Group): 1. Orthodontic patients who had an initial CBCT taken at an age greater than 18 years and underwent a follow-up CBCT after more than one year of observation.

Exclusion criteria

Exclusion criteria: Exclusion Criteria for the Experimental Group (PAOO + Orthodontics Group): 1. History of prior full-mouth fixed/clear aligner orthodontic treatment or combined orthodontic-orthognathic surgery treatment. 2. Missing maxillary anterior teeth, history of dental trauma, or presence of supernumerary teeth. 3. Active periodontal disease or chronically poor oral hygiene. 4. Severe systemic diseases such as osteoporosis, hyperthyroidism, or hypothyroidism. 5. History of smoking. Exclusion Criteria for the Positive Control Group (Orthodontics Only Group): 1. Same as the Experimental Group. Exclusion Criteria for the Negative Control Group: 1. Presence of malocclusion or history of orthodontic/orthodontic-orthognathic combined treatment prior to or between the two imaging time points. 2. Missing maxillary anterior teeth, history of dental trauma, or presence of supernumerary teeth. 3. Periodontal disease, poor oral hygiene, or history of smoking. 4. Severe systemic diseases such as osteoporosis, hyperthyroidism, or hypothyroidism.

Design outcomes

Primary

MeasureTime frame
alveolar bone thickness;Orthodontic tooth movement distance of corwn and;Cephalometric analysis according to Shanghai Ninth People's Hospital;alveolar bone height;alveolar bone density;the length and volume of root;

Secondary

MeasureTime frame
Basic information;

Countries

China

Contacts

Public ContactJiang Shijie

Stomatology Hospital,Zhejiang University School Medicine

7512029@zju.edu.cn+86 571 87213650

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 23, 2026