Coronary atherosclerotic heart disease
Conditions
Interventions
High-frequency QRS electrocardiogram analysis observation group:None
Sponsors
Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Patients diagnosed with coronary heart disease through coronary angiography; 3. LVEF < 50%; 4. Voluntary participation, signing the informed consent form, and adhering to the confidentiality agreement; 5. Any one of the following conditions qualifies as the ICD group, and any one of the following conditions does not qualify as the non-ICD group; 6. NYHA II-III grade, LVEF <= 35%, having received the best drug treatment for more than 3 months; 7. NYHA I grade, LVEF <= 30%, having received the best drug treatment for more than 3 months; 8. NYHA I grade, LVEF <= 40%, having received the best drug treatment for more than 3 months, and having non-continuous ventricular tachycardia and inducing continuous ventricular tachycardia through electrophysiological examination.
Exclusion criteria
Exclusion criteria: 1. Survivors who have previously experienced persistent ventricular tachycardia, ventricular fibrillation, or cardiac arrest; 2. Those who have previously had a cardiac implantable electronic device implanted; 3. Unplanned surgical procedures; 4. Severe liver dysfunction: AST-ALT upper limit of normal value is more than 3 times; Severe kidney dysfunction: Glomerular filtration rate < 30 mL/min/1.73m^2; 5. Advanced cancer or other major comorbidities with an expected lifespan of less than 1 year; 6. Pregnant or lactating (breastfeeding) women; 7. Alcohol abuse or mental and psychological disorders; Malnutrition: Body mass index <= 18 kg/m^2; 8. Other situations where the investigators consider the subjects to be unsuitable for participation in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major arrhythmia events, including persistent ventricular tachycardia, ventricular fibrillation, correct ICD discharge and sudden cardiac death events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventricular fibrillation;Appropriate ICD discharge;Intracranial hemorrhage;Acute heart failure;Sustained ventricular arrhythmia;Unexplained syncope;Sudden cardiac death;Major cardiovascular event;Newly onset atrial fibrillation;All-cause mortality; | — |
Countries
China
Contacts
Public ContactHua Wei
Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed