None
Conditions
Interventions
Test Group:D1–D10: Investigational product (nut oatmeal crisp) plus supplementary diet, with dietary composition adhering to the Chinese Expert Consensus on Ketogenic Diet Intervention for Type 2 Diab
Sponsors
The First Hospital of Northwestern University
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Aged 20 to 45 years, inclusive, any sex; 2. No use of any medications affecting lipid metabolism or body weight within the past 3 months; 3. No adherence to special dietary regimens (e.g., ketogenic diet, low-carbohydrate diet) within the past 3 months; 4. Voluntary provision of written informed consent.
Exclusion criteria
Exclusion criteria: 1. Exclude individuals with a BMI 35 kg/m^2; 2. Exclude the following metabolic subjects (contraindicated populations): type 1 diabetes, gestational diabetes, carnitine deficiency, carnitine palmitoyltransferase I or II deficiency, carnitine transferase II deficiency, fatty acid ß-oxidation deficiency, medium-chain acyl-CoA dehydrogenase deficiency, long-chain acyl-CoA dehydrogenase deficiency, short-chain acyl-CoA dehydrogenase deficiency, long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, medium-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, pyruvate carboxylase deficiency, porphyria; 3. Individuals with liver or kidney dysfunction; 4. Pregnant women, breastfeeding women, or those planning pregnancy in the near future; 5. Individuals allergic to components of the test food (such as nuts); 6. Individuals who are currently infected or in very poor physical condition; 7. Individuals currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood ketone concentration (ß-hydroxybutyrate); | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight, waist circumference, and BMI; | — |
Countries
China
Contacts
Public ContactFeng Zhang
The First Hospital of Northwestern University
Outcome results
None listed