Burn injury
Conditions
Interventions
Sponsors
Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Meet the diagnostic criteria for severe burns: The total burn area is 31% - 50% of total body surface area (TBSA), or the area of third-degree burns is 11% - 20% of TBSA, or the total area or the area of second-degree burns do not fall within the above ranges, but there is already shock, inhalation injury, or multiple injuries. 3. Admission within 24 hours after injury.
Exclusion criteria
Exclusion criteria: 1. Suffering from severe oral diseases (cavities, periodontal disease, oral abscesses, oral mucosal diseases, oral cancer); 2. Already had infectious diseases upon admission, including but not limited to wound infections from burns, pneumonia, urinary tract infections, etc.; 3. Patients with autoimmune diseases, immunodeficiency diseases or low immune function; 4. Had continuous use of antibiotics or hormones within 48 hours before admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral microbiota characteristics;The incidence of sepsis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of stay in the ICU;Total hospital stay;Duration of mechanical ventilation;30-day all-cause mortality rate;7-day all-cause mortality rate;Complications; | — |
Countries
China
Contacts
Public ContactLi Lin
Fujian Medical University Union Hospital
Outcome results
None listed