gastric cancer
Conditions
Interventions
Immunotherapy + Baduanjin group:Baduanjin
Immunotherapy:NA
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Age>= 18 years old, gender not limited; 2.Body weight > 45 kg; 3. Patients with advanced gastric malignant tumors, with clear pathological evidence; 4. Have not received systemic treatment before and are planned to receive first-line chemotherapy combined with immunotherapy; 5.ECOG score: 0-1, KPS score: 80-100; 6. Expected survival period >= 6 months; 7.Good compliance, voluntarily participate in this trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those with severe and uncontrolled organic lesions or infections, such as severe heart, lung or kidney failure, etc. 2.Those with severe psychological or physical functional disorders and unable to participate in physical exercise; 3. Those with brain trauma and intracranial hypertension; 4.The pain of the subjects is related to tumor emergencies such as intestinal obstruction/perforation, spinal cord compression, epidural metastasis or weight-bearing bone fractures or impending fractures; 5. Those with a history of autoimmune diseases; 6.Those with liver dysfunction (ALT >= 5×ULN, AST >= 5×ULN, TBIL>= 3×ULN) or kidney dysfunction (Cr>= 2.5×ULN); 7. Pregnant or lactating women; 8.Situations where the researcher deems the subject unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokine Inflammation Index;Immunotherapy response rate: Complete Response (CR), Partial Response (PR), Stable Disease (SD), and Progressive Disease (PD).;Assessment scale;Survival analysis: overall survival (OS) and progression-free survival (PFS) within 2 years.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection of transcription factors in gastric cancer tissue;Serum metabolomics analysis;Assessment of treatment-related toxicities and adverse reactions; | — |
Countries
China
Contacts
Public ContactQing Li
Xuzhou Central Hospital
Outcome results
None listed