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Study on the Long-Term Real-World Efficacy, Choroidal Biomarkers and Withdrawal Strategies of Repeated Low-Level Red-Light (RLRL) Therapy for Myopia

Study on the Long-Term Real-World Efficacy, Choroidal Biomarkers and Withdrawal Strategies of Repeated Low-Level Red-Light (RLRL) Therapy for Myopia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122781
Enrollment
Unknown
Registered
2026-04-17
Start date
2026-04-17
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

Continuous treatment group:None
Discontinuation group:None
Switching group:None

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Received RLRL treatment at our hospital during the study period; 2.Have verifiable baseline data and at least 1 post-treatment follow-up visit; 3.Have baseline and follow-up data of at least either AL or SER; 4.For those included in the imaging analysis, have interpretable baseline and follow-up OCT data; 5.For those included in the withdrawal strategy analysis, have a clear time node of treatment discontinuation or switching;

Exclusion criteria

Exclusion criteria: 1.Poor image quality, uncorrectable segmentation errors, or missing key variables; 2.Unverifiable RLRL exposure or treatment discontinuation/switching information; 3.Complicated with binocular vision dysfunction such as amblyopia and strabismus; 4.Suffering from other severe ocular or systemic diseases; 5.Obvious logical errors in core clinical medical records;

Design outcomes

Primary

MeasureTime frame
Annualized axial length (AL) change rate (mm/year);Annualized spherical equivalent refraction (SER) change rate (D/year);

Secondary

MeasureTime frame
The changes of choroidal thickness (central, 3 mm nasal, 3 mm temporal) and luminal area (LA) in each region;

Countries

China

Contacts

Public ContactLu Yi

Shanghai General Hospital

yiyiscorpio@163.com+86 21 63240090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026