FindTrial
Sign In

Posterior Left Pericardiotomy for Prevention of New-Onset Atrial Fibrillation After Off-Pump Coronary Artery Bypass Grafting: A Single-Center Randomized Controlled Trial

Posterior Left Pericardiotomy for Prevention of New-Onset Atrial Fibrillation After Off-Pump Coronary Artery Bypass Grafting: a single-center, superiority, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122768
Enrollment
Unknown
Registered
2026-04-17
Start date
2026-04-20
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease (CAD)

Interventions

Experimental group:Experimental group (Posterior pericardial window group) Before chest closure during standard off-pump coronary artery bypass grafting (OPCABG), a 4-5 cm vertical incision is made in
Control group:Control group (Standard surgery group / Sham control) After standard off-pump coronary artery bypass grafting (OPCABG), a sham incision is simulated at the corresponding pericardial site

Sponsors

Beijing Anzhen Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Scheduled to undergo off-pump coronary artery bypass grafting (OPCABG); 2. No history of atrial fibrillation/flutter before surgery; 3. Age >= 18 years.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; 2. History of prior pericardial surgery or severe pleural adhesions; 3. End-stage renal disease (eGFR = 50 mm; 7. Left ventricular ejection fraction (LVEF) < 35%.

Design outcomes

Primary

MeasureTime frame
Incidence of new-onset postoperative atrial fibrillation (POAF) within 7 days after surgery;—

Secondary

MeasureTime frame
Incidence of major adverse cardiovascular and cerebrovascular events (MACCE);—

Countries

China

Contacts

Public ContactXiubin Yang

Beijing Anzhen Hospital, Capital Medical University

xiubinyang@hotmail.com+86 131 2021 7021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026