ventilator-induced diaphragmatic dysfunction
Conditions
Interventions
dose-response group:By using a non-invasive diaphragm nerve electrical stimulation device, the stimulation intensity is gradually adjusted during the stimulation process until the final intensity is r
efficacy group:By using a non-invasive diaphragm nerve electrical stimulation device, during the stimulation process, the support of the ventilator was gradually reduced to maintain the patient's tida
Sponsors
Sanbo Brain Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age >=18 years; 2. Receiving MV; 3. BMI <30 kg/m²; 4. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients at risk of phrenic nerve injury or dysfunction (e.g., history of neck surgery, neuromuscular diseases, severe COPD, etc.) ; 2. Patients with implanted pacemakers, severe arrhythmias, or heart failure (NYHA class III-IV) ; 3. BMI > 30 kg/m² ; 4. Pregnant or breastfeeding women ; 5. Patients with multiple organ failure ; 6. Pneumothorax ; 7. Patients with active tuberculosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| tidal volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| airway pressure-time ;flow-time;ECG;SpO2; | — |
Countries
China
Contacts
Public ContactShi Zhonghua
Sanbo Brain Hospital, Capital Medical University
Outcome results
None listed