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Clinical epidemiology, drug treatment mode, and disease progression association study of chronic hepatitis B in large tertiary hospitals: based on real-world electronic medical record data

Clinical epidemiology, drug treatment mode, and disease progression association study of chronic hepatitis B in large tertiary hospitals: based on real-world electronic medical record data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122758
Enrollment
Unknown
Registered
2026-04-17
Start date
2026-04-20
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with chronic hepatitis B, including chronic hepatitis B, hepatitis B cirrhosis (compensated or decompensated), hepatitis B-related hepatocellular carcinoma (HCC), hepatitis B with metabolic associated fatty liver disease (MAFLD), etc

Interventions

Observation group:None

Sponsors

Xixi Hospital of Hangzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years old; 2.Patients diagnosed with chronic hepatitis B according to the "Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2022 Edition)" include those with chronic hepatitis B, hepatitis B-related cirrhosis (compensated or decompensated stage), hepatitis B-associated hepatocellular carcinoma (HCC), and hepatitis B combined with metabolic associated fatty liver disease (MAFLD); 3.The EMR system records are complete, including the initial diagnosis and at least one follow-up data entry; 4.The data can be traced back to 2018, and the latest follow-up data is available before 2025;

Exclusion criteria

Exclusion criteria: 1.Other major pathogenic chronic liver diseases, such as hepatitis C/D, autoimmune liver diseases (AIH, PBC, PSC), genetic metabolic liver diseases (Wilson's disease, hemochromatosis, etc.); 2.Drug induced liver injury (DILI) caused by non anti hepatitis B virus drugs is clinically determined to be related to drugs; 3.Acute hepatitis B or inactive HBsAg carriers; 4.Serious data missing or follow-up time<6 months; 5.Liver transplantation or other major interventions that may affect the natural course and treatment outcome of hepatitis B during the study period;

Design outcomes

Primary

MeasureTime frame
ALT?AST?HBV DNA?HBsAg?PLT,etc;

Secondary

MeasureTime frame
Types of antiviral drugs;

Countries

China

Contacts

Public ContactZhou Jing

Xixi Hospital of Hangzhou

amt16888@163.com+86 571 86481623

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026