postoperative sleep disturbances
Conditions
Interventions
Remimazolam group:Remimazolam anesthesia
Sponsors
Renshou County People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing laparoscopic cholecystectomy under general anaesthesia with endotracheal intubation; the estimated duration of surgery is within 1 hour; 2. Aged 18–64 years; gender is not restricted; 3. ASA Class I–II; 4. BMI between 18 kg/m² and 30 kg/m²; 5. Pittsburgh Sleep Quality Index (PSQI) score <= 7, Athens Insomnia Scale (AIS) score < 4; 6. Hospital Anxiety and Depression Scale (HADS) score <= 7; 7. Informed consent: voluntary participation in this trial, with the patient personally signing the informed consent form
Exclusion criteria
Exclusion criteria: 1. Patients unable to complete the Pittsburgh Sleep Quality Index (PSQI), the Athens Insomnia Scale (AIS) or the Hospital Anxiety and Depression Scale (HADS); 2. Patients with severe concomitant cardiovascular, cerebrovascular, hepatic or renal disease; 3. Patients receiving long-term treatment with opioid analgesics, sedatives or non-steroidal anti-inflammatory drugs; 4. Patients with a history of mental illness; 5. Patients who have participated in other drug or device clinical trials within the three months prior to the screening period; 6. Patients deemed unsuitable for this clinical trial by the investigator; 7. Patients unwilling to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index (PSQI) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Athens Insomnia Scale (AIS) scores;Resting Visual Analog Scale (VAS) pain scores;C-reactive protein (CRP) levels;Neutrophil and lymphocyte counts;Duration of surgery;Hemodynamic parameters; | — |
Countries
China
Contacts
Public ContactDanni Li
Renshou County People's Hospital
Outcome results
None listed