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Adolescent Depression From a Brain-Gut Axis Perspective: A Multi-Omics Study on Interaction Mechanisms Among Neuroimaging, Systemic Metabolites, and Gut Metagenomics

Adolescent Depression From a Brain-Gut Axis Perspective: A Multi-Omics Study on Interaction Mechanisms Among Neuroimaging, Systemic Metabolites, and Gut Metagenomics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122737
Enrollment
Unknown
Registered
2026-04-17
Start date
2026-04-17
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive symptoms of primary psychotic disorders

Interventions

Control group:None
Case group:None

Sponsors

Wuxi Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients with depressive episodes;

Exclusion criteria

Exclusion criteria: 1.Patients with bipolar disorder; 2.Patients with schizophrenia; 3.History of Substance abuse; 4.During pregnancy or lactation; 5.Severe internal diseases (such as abnormal coagulation function, etc. 6.a history of craniocerebral trauma that leads to loss of consciousness or a history of epilepsy; 7.fever, acute infection, and infectious diseases;

Design outcomes

Primary

MeasureTime frame
Brain magnetic resonance imaging;Fecal metagenomics and metabolites;Serum metabolites?cytokines;—

Secondary

MeasureTime frame
Saliva metabolites;—

Countries

China

Contacts

Public ContactFei Wang;Zhijia Li

Wuxi Mental Health Center

394130203@qq.com+86 513 8879 0530

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026