Patients with Sjögren's syndrome meet the 2016 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria, which include: clinically manifest xerostomia (patients report significant dry mouth lasting =3 months) along with reduced salivary gland function, or diagnosis confirmed by salivary gland biopsy/anti-SSA antibody testing.
Conditions
Interventions
Pre-experiment group:Comprehensive Management Strategy for Oral Frailty in Patients with Sj?gren's Syndrome
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients aged >= 18 years who meet the 2016 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for Sjögren's syndrome. 2.Patients are able to cooperate with relevant examinations and follow-up. 3.Both genders are included; considering the higher prevalence of Sjögren's syndrome in women, efforts will be made to ensure a representative gender ratio.
Exclusion criteria
Exclusion criteria: 1.Comorbid other autoimmune diseases, such as systemic lupus erythematosus, systemic scleroderma, etc.; 2.Use of medications that affect salivary secretion, such as anticholinergics, antidepressants, antihistamines, etc., in the recent period (within the last 3 months); 3.Presence of active oral infection, severe periodontal disease, oral malignancy, or oral mucosal lesions; 4.Pregnant or breastfeeding women; 5.Patients with cognitive impairment or mental disorders, making it difficult to cooperate with the study procedures; 6.Presence of severe systemic diseases, such as severe cardiopulmonary, hepatic, or renal insufficiency, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unstimulated salivary flow rate;Oral Frailty Index-8, OFI-8;Fatigue,Resistance,Ambulation,Illness,and Loss, FRAIL;Decay Missing Fill, DMFT; | — |
Countries
China
Contacts
Public ContactAdalia
Beijing Hospital
Outcome results
None listed